Case studies.

A digital twin of patient cohorts, with HIPAA-grade provenance and a decision engine that refuses silent writes.

• ·94% precision on cohort matching against clinician-annotated holdout
• ·7× speed-up on RWE feasibility studies vs the previous manual flow
• ·Full chain-of-custody for every cohort revision

Seven-day simulation of real disruption patterns — OSINT noise, adversarial misinformation, and a structured risk decision.

• ·Agent 007 case with 112 submissions from 24 teams
• ·Top agent hit 74.2 composite across eight evaluators
• ·Methodology replicated by two partner teams in their own environments